Leonard Herzenberg (November 5, 1931 – October 27, 2013)
Tuesday, December 3, 2013
In recognition of an innovator in immunology: Leonard Herzenberg, inventor of the FACS machine.
Immunologist,
geneticist, and philanthropist Dr. Leonard Herzenberg profoundly changed cell
biology and immunology with the invention of the fluorescence-activated cell sorter (FACS ) machine. Herzenberg created the
biotechnology in 1970, driven by the need for quantification of cell types
during his novel work with hybridomas, which are monoclonal antibody producing
B cells fused with cancer cells. The
FACS, also referred to as a flow cytometer, allows scientists to sort,
quantify, and identify different cells types, and has been vital to the field
ever since its existence. Not only did
his seminal biotechnology and research significantly advance what is known
about lymphocyte biology, he used the royalties from the FACS to further fund
his own research. Dr. Herzenberg’s ground
breaking achievements earned him an array of awards, most notably the Kyoto
Prize, a Japanese equivalent to the Nobel Prize. His priceless contributions will
continue to impact basic science research indefinitely.
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